| Item Type | Name |
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Academic Article
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Association of the tissue kallikrein gene promoter with ESRD and hypertension.
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Academic Article
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Linkage heterogeneity of end-stage renal disease on human chromosome 10.
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Academic Article
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Impact of birth weight on familial aggregation of end-stage renal disease.
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Academic Article
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Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression.
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Academic Article
|
Susceptibility genes for hypertension and renal failure.
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Academic Article
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Comparative genomic analysis of the HNF-4alpha transcription factor gene.
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Academic Article
|
A genome-wide scan for type 2 diabetes in African-American families reveals evidence for a locus on chromosome 6q.
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Academic Article
|
The importance of family history on the development of renal disease.
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Academic Article
|
Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes.
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Academic Article
|
Linkage analysis of diabetes status among hypertensive families: the Hypertension Genetic Epidemiology Network study.
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Academic Article
|
The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility.
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Academic Article
|
The Family Investigation of Nephropathy and Diabetes (FIND): design and methods.
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Academic Article
|
T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study.
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Academic Article
|
The familial clustering of renal disease and related phenotypes.
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Academic Article
|
Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes.
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Academic Article
|
P-selectin gene haplotype associations with albuminuria in the Diabetes Heart Study.
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Academic Article
|
Genetic analysis of the GLUT10 glucose transporter (SLC2A10) polymorphisms in Caucasian American type 2 diabetes.
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|
Academic Article
|
Recent progress in inherited kidney diseases.
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Academic Article
|
Genetic susceptibility contributes to renal and cardiovascular complications of type 2 diabetes mellitus.
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Academic Article
|
Obesity is associated with family history of ESRD in incident dialysis patients.
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Academic Article
|
A functional polymorphism in the lymphotoxin-alpha gene is associated with carotid artery wall thickness: the Diabetes Heart Study.
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Academic Article
|
Genome scan of glomerular filtration rate and albuminuria: the HyperGEN study.
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Academic Article
|
A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans.
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Academic Article
|
Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy.
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Academic Article
|
Association of the proprotein convertase subtilisin/kexin-type 2 (PCSK2) gene with type 2 diabetes in an African American population.
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Academic Article
|
Genetic factors in diabetic nephropathy.
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Academic Article
|
Comprehensive evaluation of the estrogen receptor alpha gene reveals further evidence for association with type 2 diabetes enriched for nephropathy in an African American population.
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Academic Article
|
Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations in type 2 diabetes patients with nephropathy from an African-American population.
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Academic Article
|
Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease.
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Academic Article
|
Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study.
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Academic Article
|
Evaluation of genetic association and expression reduction of TRPC1 in the development of diabetic nephropathy.
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Academic Article
|
Relationship between genetic variants in myocardial sodium and potassium channel genes and QT interval duration in diabetics: the Diabetes Heart Study.
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Academic Article
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The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans.
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Academic Article
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Bone morphogenetic protein 7 (BMP7) gene polymorphisms are associated with inverse relationships between vascular calcification and BMD: the Diabetes Heart Study.
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Academic Article
|
Gene-gene and gene-environment interactions in HIV-associated nephropathy: A focus on the MYH9 nephropathy susceptibility gene.
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Academic Article
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Is collapsing C1q nephropathy another MYH9-associated kidney disease? A case report.
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Academic Article
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Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy.
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Academic Article
|
A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes.
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Academic Article
|
The spectrum of MYH9-associated nephropathy.
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Academic Article
|
Genetics and the kidney: promise, potential, and challenges. Introduction.
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Academic Article
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Genetic basis of nondiabetic end-stage renal disease.
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Academic Article
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Progression of chronic kidney disease: Adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis.
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Academic Article
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Potential effects of MYH9-associated nephropathy on dialysis and kidney transplant outcomes.
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Academic Article
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Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.
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Academic Article
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Analysis of candidate genes on chromosome 20q12-13.1 reveals evidence for BMI mediated association of PREX1 with type 2 diabetes in European Americans.
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Academic Article
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Coincident idiopathic focal segmental glomerulosclerosis collapsing variant and diabetic nephropathy in an African American homozygous for MYH9 risk variants.
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Academic Article
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Correlates of coronary artery calcified plaque in blacks and whites with type 2 diabetes.
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Academic Article
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Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study.
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Academic Article
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The impact of FADS genetic variants on ?6 polyunsaturated fatty acid metabolism in African Americans.
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Academic Article
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Meta-analysis of genome-wide linkage scans for renal function traits.
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Academic Article
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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
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Academic Article
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Genome-wide association of BMI in African Americans.
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Academic Article
|
Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans.
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Academic Article
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Target organ damage in African American hypertension: role of APOL1.
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Academic Article
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Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy.
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Academic Article
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Evaluation of TRAF6 in a large multiancestral lupus cohort.
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Academic Article
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The new era of APOL1-associated glomerulosclerosis.
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Academic Article
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Effect of race and genetics on vitamin D metabolism, bone and vascular health.
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Academic Article
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Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans.
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Academic Article
|
Relevance of the ACTN4 gene in African-Americans with non-diabetic end-stage renal disease.
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Academic Article
|
Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complications.
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Academic Article
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Informed conditioning on clinical covariates increases power in case-control association studies.
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Academic Article
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Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study.
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Academic Article
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Admixture mapping of coronary artery calcified plaque in African Americans with type 2 diabetes mellitus.
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Academic Article
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An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.
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Academic Article
|
MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
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Academic Article
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End-stage renal failure in African Americans: insights in kidney disease susceptibility.
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Academic Article
|
Heritability of carotid artery intima-medial thickness in type 2 diabetes.
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Academic Article
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Evaluation of genetic variation and association in the matrix metalloproteinase 9 (MMP9) gene in ESRD patients.
|
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Academic Article
|
Nucleotide variation, haplotype structure, and association with end-stage renal disease of the human interleukin-1 gene cluster.
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Academic Article
|
A genome scan for diabetic nephropathy in African Americans.
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Academic Article
|
A genome scan for ESRD in black families enriched for nondiabetic nephropathy.
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Academic Article
|
Association of an insulin gene promoter insertion polymorphism with type 2 diabetes and diabetic nephropathy in African Americans.
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Academic Article
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A genome scan for all-cause end-stage renal disease in African Americans.
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Academic Article
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Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis.
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Academic Article
|
Genetic factors in end-stage renal disease.
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Academic Article
|
Association of the mu-opioid receptor gene with type 2 diabetes mellitus in an African American population.
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Academic Article
|
Genetic determinants of albuminuria and renal disease in diabetes mellitus.
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Academic Article
|
Genetics of progressive renal failure in diabetic kidney disease.
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|
Academic Article
|
Quantitative trait loci on chromosome 8q24 for pancreatic beta-cell function and 7q11 for insulin sensitivity in obese nondiabetic white and black families: evidence from genome-wide linkage scans in the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) study.
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|
Academic Article
|
Variants of the CD40 gene but not of the CD40L gene are associated with coronary artery calcification in the Diabetes Heart Study (DHS).
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|
Academic Article
|
Genetic factors in common complex renal and cardiovascular diseases.
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|
Academic Article
|
Coincident linkage of type 2 diabetes, metabolic syndrome, and measures of cardiovascular disease in a genome scan of the diabetes heart study.
|
|
Academic Article
|
Investigation of the estrogen receptor-alpha gene with type 2 diabetes and/or nephropathy in African-American and European-American populations.
|
|
Academic Article
|
Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND).
|
|
Academic Article
|
Mining the genome for susceptibility to diabetic nephropathy: the role of large-scale studies and consortia.
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|
Academic Article
|
Familial clustering of chronic kidney disease.
|
|
Academic Article
|
Plasma adiponectin concentrations and correlates in African Americans in the Hypertension Genetic Epidemiology Network (HyperGEN) study.
|
|
Academic Article
|
Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND).
|
|
Academic Article
|
Association of the distal region of the ectonucleotide pyrophosphatase/phosphodiesterase 1 gene with type 2 diabetes in an African-American population enriched for nephropathy.
|
|
Academic Article
|
Association of NOS1AP genetic variants with QT interval duration in families from the Diabetes Heart Study.
|
|
Academic Article
|
Chromogranin A polymorphisms are associated with hypertensive renal disease.
|
|
Academic Article
|
Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.
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|
Academic Article
|
Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study.
|
|
Academic Article
|
Association of arachidonate 12-lipoxygenase genotype variation and glycemic control with albuminuria in type 2 diabetes.
|
|
Academic Article
|
Exploration of the utility of ancestry informative markers for genetic association studies of African Americans with type 2 diabetes and end stage renal disease.
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|
Academic Article
|
Genetic admixture: a tool to identify diabetic nephropathy genes in African Americans.
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|
Academic Article
|
MYH9 is associated with nondiabetic end-stage renal disease in African Americans.
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|
Academic Article
|
MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis.
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Academic Article
|
Hypertension-associated kidney disease: perhaps no more.
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Academic Article
|
Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans.
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Academic Article
|
Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping.
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|
Academic Article
|
Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group.
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|
Academic Article
|
Susceptibility genes in common complex kidney disease.
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|
Academic Article
|
Dense mapping of MYH9 localizes the strongest kidney disease associations to the region of introns 13 to 15.
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|
Academic Article
|
The acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with nephropathy in Chinese patients with type 2 diabetes.
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Academic Article
|
The non-muscle Myosin heavy chain 9 gene (MYH9) is not associated with lupus nephritis in African Americans.
|
|
Academic Article
|
Association of trypanolytic ApoL1 variants with kidney disease in African Americans.
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|
Academic Article
|
Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant.
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Academic Article
|
A genome-wide association study for diabetic nephropathy genes in African Americans.
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|
Academic Article
|
Intensive blood-pressure control in hypertensive chronic kidney disease.
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|
Academic Article
|
Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study.
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Academic Article
|
Genetic mapping of vascular calcified plaque loci on chromosome 16p in European Americans from the diabetes heart study.
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Academic Article
|
Review of the Diabetes Heart Study (DHS) family of studies: a comprehensively examined sample for genetic and epidemiological studies of type 2 diabetes and its complications.
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Academic Article
|
Effects of race on albuminuria and risk of cardiovascular and kidney disease.
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|
Academic Article
|
Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
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Academic Article
|
Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.
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Academic Article
|
Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.
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Academic Article
|
Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
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Academic Article
|
Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans.
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Academic Article
|
A genome-wide association search for type 2 diabetes genes in African Americans.
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Academic Article
|
Genetic risk assessment of type 2 diabetes-associated polymorphisms in African Americans.
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Academic Article
|
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
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Academic Article
|
Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries.
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Academic Article
|
Insights into the genetic architecture of diabetic nephropathy.
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Academic Article
|
Novel findings and future directions on the genetics of hypertension.
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Academic Article
|
Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease.
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Academic Article
|
Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
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Academic Article
|
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
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Academic Article
|
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
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Academic Article
|
Effects of rare and common blood pressure gene variants on essential hypertension: results from the Family Blood Pressure Program, CLUE, and Atherosclerosis Risk in Communities studies.
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Academic Article
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Genetic analysis of haptoglobin polymorphisms with cardiovascular disease and type 2 diabetes in the Diabetes Heart Study.
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Academic Article
|
Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
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Concept
|
Catheterization, Central Venous
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Concept
|
Glucose Tolerance Test
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Concept
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Pain Measurement
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Concept
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Absorptiometry, Photon
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Concept
|
Electrophoresis
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Concept
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Longitudinal Studies
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Concept
|
Microscopy, Fluorescence
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Concept
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Psychiatric Status Rating Scales
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Concept
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Epigenesis, Genetic
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Concept
|
Liver Transplantation
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Concept
|
Ultrasonography, Doppler, Transcranial
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Concept
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Population Surveillance
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Concept
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Diffusion Magnetic Resonance Imaging
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Concept
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Models, Genetic
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Concept
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Education, Medical
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Concept
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Blood Chemical Analysis
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Concept
|
Tomography, Spiral Computed
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Concept
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Therapies, Investigational
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Concept
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Medicare
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Concept
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Electrophoretic Mobility Shift Assay
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Concept
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Mass Screening
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Concept
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Salvage Therapy
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Concept
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Polymorphism, Genetic
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Concept
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Research Design
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Concept
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Genetic Testing
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Concept
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Amino Acid Substitution
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Concept
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Antibodies, Antinuclear
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Concept
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Health Services for the Aged
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Concept
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Epidemiologic Studies
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Concept
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Demography
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Concept
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Family
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Concept
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Magnetic Resonance Angiography
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Concept
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Renal Replacement Therapy
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Concept
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Double-Blind Method
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Concept
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Nephrectomy
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Concept
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Statistics as Topic
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Concept
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Cohort Studies
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Concept
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Databases, Genetic
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Concept
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Radiography
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Concept
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Guideline Adherence
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Concept
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Tissue and Organ Procurement
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Concept
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Renal Dialysis
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Concept
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Genetic Predisposition to Disease
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Concept
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Genetic Loci
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Concept
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Reference Standards
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Concept
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Stroop Test
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Concept
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Biopsy
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Concept
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Coronary Angiography
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Concept
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Family Characteristics
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Concept
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Dietary Supplements
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Concept
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Perfusion
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Concept
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Tissue and Organ Harvesting
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Concept
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Early Diagnosis
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Concept
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Logistic Models
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Concept
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Genetic Markers
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Concept
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Clinical Trials as Topic
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Concept
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Genetic Variation
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Concept
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Estrogen Replacement Therapy
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Concept
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Transcription, Genetic
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Concept
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Echocardiography
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Concept
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Chromatography, High Pressure Liquid
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Concept
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Hormone Replacement Therapy
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Concept
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Peritoneal Dialysis
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Concept
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Arteriovenous Shunt, Surgical
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Concept
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Mutagenesis, Insertional
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Concept
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Ultrafiltration
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Concept
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Multicenter Studies as Topic
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Concept
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Fluorescein Angiography
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Concept
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Animals, Genetically Modified
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Concept
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Administration, Topical
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Concept
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Kidney Function Tests
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Concept
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Transplantation, Homologous
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Concept
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Ultrasonography, Doppler
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Concept
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Genetic Heterogeneity
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Concept
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Hospitalization
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Concept
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Glomerular Filtration Rate
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Concept
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DNA Mutational Analysis
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Concept
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Biomedical Research
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Concept
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Donor Selection
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Concept
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Urinalysis
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Concept
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Gene Expression Profiling
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Concept
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Enzyme-Linked Immunosorbent Assay
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Concept
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Nutrition Surveys
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Concept
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Genetic Load
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Concept
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Prognosis
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Concept
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Sequence Analysis, DNA
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Concept
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Patient Selection
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Concept
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Kidney Transplantation
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Concept
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Needs Assessment
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Concept
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Imaging, Three-Dimensional
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Concept
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Health Status Indicators
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Concept
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Genetic Association Studies
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Concept
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Fasting
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Concept
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Anthropometry
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Concept
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Epistasis, Genetic
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Concept
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Magnetic Resonance Imaging
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Concept
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Mutagenesis, Site-Directed
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Concept
|
Fluorescent Antibody Technique
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Concept
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Microscopy, Electron, Transmission
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Concept
|
Genetics, Population
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Concept
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Selection, Genetic
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Concept
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Validation Studies as Topic
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Concept
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Case-Control Studies
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Concept
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Prospective Studies
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Concept
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Cross-Sectional Studies
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Concept
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Chromosome Mapping
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Concept
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Randomized Controlled Trials as Topic
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Concept
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Genome-Wide Association Study
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Concept
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Tomography, X-Ray Computed
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Concept
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Oligonucleotide Array Sequence Analysis
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Concept
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Censuses
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Concept
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Angiography
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Concept
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Polymerase Chain Reaction
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Concept
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Blood Pressure Determination
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Concept
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Neuropsychological Tests
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Concept
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Ultrasonography
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Concept
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Risk Assessment
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Concept
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Promoter Regions, Genetic
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Concept
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Surface Plasmon Resonance
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Concept
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Follow-Up Studies
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Concept
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Cloning, Molecular
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Concept
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Gene Knockdown Techniques
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Concept
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Community-Based Participatory Research
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Concept
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Cardiac-Gated Imaging Techniques
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Concept
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Electrocardiography
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Concept
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Mendelian Randomization Analysis
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Concept
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Infection Control
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Concept
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Critical Care
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Academic Article
|
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
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Academic Article
|
Diabetic nephropathy: FRMD3 in diabetic nephropathy--guilt by association.
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Academic Article
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Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.
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Academic Article
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Impact of HDL genetic risk scores on coronary artery calcified plaque and mortality in individuals with type 2 diabetes from the Diabetes Heart Study.
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|
Academic Article
|
Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
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Academic Article
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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
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Academic Article
|
PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
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Academic Article
|
APOL1 and progression of nondiabetic nephropathy.
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|
Academic Article
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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
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Academic Article
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ABIN1 dysfunction as a genetic basis for lupus nephritis.
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Academic Article
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JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy.
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Academic Article
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Population ancestry and genetic risk for diabetes and kidney, cardiovascular, and bone disease: modifiable environmental factors may produce the cures.
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Academic Article
|
APOL1 risk variants, race, and progression of chronic kidney disease.
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|
Academic Article
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Genetic analysis of adiponectin variation and its association with type 2 diabetes in African Americans.
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Academic Article
|
Common variants in Mendelian kidney disease genes and their association with renal function.
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|
Academic Article
|
Perceptions regarding genetic testing in populations at risk for nephropathy.
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Academic Article
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Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
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|
Academic Article
|
Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study.
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Academic Article
|
Association of low-grade albuminuria with adverse cardiac mechanics: findings from the hypertension genetic epidemiology network (HyperGEN) study.
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Academic Article
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Gene-gene interactions in APOL1-associated nephropathy.
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Academic Article
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Genetics in kidney disease in 2013: Susceptibility genes for renal and urological disorders.
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Academic Article
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Generalizability of genetic findings related to kidney function and albuminuria.
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Academic Article
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A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND).
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Academic Article
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Analysis of coding variants identified from exome sequencing resources for association with diabetic and non-diabetic nephropathy in African Americans.
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Academic Article
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End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.
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Academic Article
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Improving CKD therapies and care: a National Dialogue.
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Academic Article
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Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.
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Academic Article
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Genetic risk score associations with cardiovascular disease and mortality in the Diabetes Heart Study.
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Academic Article
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Heritability and genetic association analysis of cognition in the Diabetes Heart Study.
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Academic Article
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Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
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Academic Article
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Analysis of common and coding variants with cardiovascular disease in the Diabetes Heart Study.
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Academic Article
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Gene-gene and gene-environment interactions in apolipoprotein L1 gene-associated nephropathy.
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Academic Article
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Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
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Academic Article
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Coding variants in nephrin (NPHS1) and susceptibility to nephropathy in African Americans.
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Academic Article
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The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease.
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Academic Article
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Apolipoprotein L1 gene variants associate with prevalent kidney but not prevalent cardiovascular disease in the Systolic Blood Pressure Intervention Trial.
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Academic Article
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Histopathologic findings associated with APOL1 risk variants in chronic kidney disease.
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Academic Article
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The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
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Academic Article
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Risk factors: familial aggregation of ESRD in Europeans-is it in the genes?
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Academic Article
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Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity.
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Academic Article
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A comparison of type 2 diabetes risk allele load between African Americans and European Americans.
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Academic Article
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Heritability and genetic association analysis of neuroimaging measures in the Diabetes Heart Study.
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Academic Article
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Should kidney donors be genotyped for APOL1 risk alleles?
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Academic Article
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Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
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Academic Article
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APOL1 and kidney disease: new insights leading to novel therapies.
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Academic Article
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Analysis of a cardiovascular disease genetic risk score in the Diabetes Heart Study.
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Academic Article
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Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells.
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Academic Article
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Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3'-Untranslated Region Polymorphism C+87T by MicroRNA-107.
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Academic Article
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Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND).
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Academic Article
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Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation.
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Academic Article
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Re-Sequencing of the APOL1-APOL4 and MYH9 Gene Regions in African Americans Does Not Identify Additional Risks for CKD Progression.
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Academic Article
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Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
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Academic Article
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Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.
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Academic Article
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Characterization of circulating APOL1 protein complexes in African Americans.
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Academic Article
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Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
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Academic Article
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Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.
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Academic Article
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Genetic analysis of advanced glycation end products in the DHS MIND study.
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Academic Article
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Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND).
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Academic Article
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Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American-Diabetes Heart Study.
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Academic Article
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APOL1 nephropathy risk variants are associated with altered high-density lipoprotein profiles in African Americans.
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Academic Article
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Association Analysis of the Cubilin (CUBN) and Megalin (LRP2) Genes with ESRD in African Americans.
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Academic Article
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Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.
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Academic Article
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Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans.
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Academic Article
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The genetic architecture of type 2 diabetes.
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Academic Article
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Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
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Academic Article
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APOE Genotypes Associate With Cognitive Performance but Not Cerebral Structure: Diabetes Heart Study MIND.
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Academic Article
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Genetics: Genetic factors in the regulation of blood pressure.
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Academic Article
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Association of kidney structure-related gene variants with type 2 diabetes-attributed end-stage kidney disease in African Americans.
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Grant
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Cerebrovascular Disease and Cognitive Performance in African Americans
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Grant
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Subclinical CVD in African American Type 2 Diabetics
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Grant
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Genetic Determinants of Renal Transplant Survival from African American Donors
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Grant
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Natural History of MYH9-Associated Nephropathy
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Grant
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Continuation of the FIND Study
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Grant
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GENETIC ANALYSIS OF HUMAN HYPERTENSIVE ESRD
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Grant
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An Integrative Genomic Approach to APOL1-Associated Nephropathy.
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Academic Article
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Genetic epidemiology in kidney disease.
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Academic Article
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The Apolipoprotein L1 Gene and Cardiovascular Disease.
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Academic Article
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A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
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Academic Article
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A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.
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Academic Article
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Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.
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Academic Article
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A tripartite complex of suPAR, APOL1 risk variants and avß3 integrin on podocytes mediates chronic kidney disease.
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Academic Article
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Genetic regulation of adipose tissue transcript expression is involved in modulating serum triglyceride and HDL-cholesterol.
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Academic Article
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Transancestral mapping and genetic load in systemic lupus erythematosus.
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Grant
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Wake Forest APOLLO Scientific and Data Research Center
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Academic Article
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Apolipoprotein L1 Gene Effects on Kidney Transplantation.
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Academic Article
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Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
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Academic Article
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Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.
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Academic Article
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Characterization of Coding/Noncoding Variants for SHROOM3 in Patients with CKD.
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Academic Article
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Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.
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Academic Article
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Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations.
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Academic Article
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A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
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Academic Article
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Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
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Academic Article
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Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans.
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Academic Article
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Response to Comment on Chan et al. FGF23 Concentration and APOL1 Genotype Are Novel Predictors of Mortality in African Americans With Type 2 Diabetes. Diabetes Care 2018;41:178-186.
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Academic Article
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
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Academic Article
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Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III.
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Academic Article
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A catalog of genetic loci associated with kidney function from analyses of a million individuals.
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Academic Article
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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.
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Academic Article
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APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis.
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Academic Article
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Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.
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Academic Article
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APOL1-Associated Nephropathy: A Key Contributor to Racial Disparities in CKD.
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Academic Article
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Apolipoprotein L1 Testing in African Americans: Involving the Community in Policy Discussions.
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Academic Article
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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale.
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Academic Article
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Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
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Academic Article
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Practical Considerations for APOL1 Genotyping in the Living Kidney Donor Evaluation.
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Academic Article
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HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.
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Academic Article
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Inherited causes of clonal haematopoiesis in 97,691 whole genomes.
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Academic Article
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Gene Set Enrichment Analsyes Identiify Pathways Involved in Genetic Risk for Diabetic Retinopathy.
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Academic Article
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Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.
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Academic Article
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Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.
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